Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats
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چکیده
منابع مشابه
Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats
BACKGROUND Advanced glycation end products (AGEs) have been proposed to be involved in pulmonary fibrosis, but its role in this process has not been fully understood. To investigate the role of AGE formation in pulmonary fibrosis, we used a bleomycin (BLM)-stimulated rat model treated with aminoguanidine (AG), a crosslink inhibitor of AGE formation. METHODS Rats were intratracheally instilled...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2009
ISSN: 1465-993X
DOI: 10.1186/1465-9921-10-55